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Prevalence of Irritable Bowel Syndrome and Depression in Fibromyalgia
Authors:Jayde E Kurland MD  FACP  Walter J Coyle MD  FACP  FACG  Anne Winkler MD  PhD  FACP  FACR  Elizabeth Zable MD  FACR
Institution:(1) Department of Gastroenterology, Naval Medical Center San Diego, San Diego, California;(2) St. John’s Physicians and Clinics, Springfield, Missouri;(3) University Community Hospital, Tampa, Florida, USA;(4) 1116 Reserve Champion Dr., Rockville, MD, 20850
Abstract:The purpose of this study was to determine the point prevalence of depressive symptoms, using the PRIME-MD questionnaire, and irritable bowel syndrome (IBS), while comparing the Rome II to the Rome I criteria, in patients with fibromyalgia (FM) and rheumatologic controls in an outpatient setting. The prevalence of IBS in FM patients (n = 105) was 63% by Rome I and 81% by Rome II criteria. The prevalence of IBS in controls (n = 62) was 15% by Rome I and 24% by Rome II criteria (FM vs. control; P < 0.001). Depressive symptoms were met in 40% of FM patients and 8% of controls (P < 0.001). The coexistence of IBS and depressive symptoms in the FM patients was 31% (Rome I) and 34% (Rome II). The prevalence of IBS and depressive symptoms was higher in FM patients compared to the control population. Identification of IBS and depressive symptoms in FM patients might enable clinicians to better meet the needs of this patient population. The views expressed in this article are those of the authors and do not reflect the official policy or practice of the Department of the Navy, Department of Defense, or the United States Government. This research was performed at outpatient private rheumatology clinics. No financial support was received for the research
Keywords:fibromyalgia  irritable bowel syndrome  depression  Rome I criteria  Rome II criteria
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