| 4项指标联合检测诊断冠心病的临床价值 |
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| 引用本文： | 林志芳,岑丽莲,柯尊彬,贾冰,李海珠,帅虎,梅敏.4项指标联合检测诊断冠心病的临床价值[J].检验医学与临床,2008,5(13):781-782. |
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| 作者姓名： | 林志芳 岑丽莲 柯尊彬 贾冰 李海珠 帅虎 梅敏 |
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| 作者单位： | 广东省肇庆市第一人民医院检验科,526021 |
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| 摘 要： | 目的探讨同型半胱氨酸（tHey）、超敏C反应蛋白（hs-CRP）、脂蛋白（a）Lp（a）]和D-二聚体（DD）与冠心病的关系。方法检测160例冠心病患者血清tHey、hs-CRP、Lp（a）和血浆DD水平，并选择健康人群80例作为对照组。结果冠心病患者血清tHey、hs-CRP、Lp（a）和血浆DD水平显著高于健康对照组（P〈0．05）。结论联合检测血清tHey、hs-CRP、Lp（a）和血浆DD水平的变化，对冠心病的预防和早期诊断及动态监测有着十分重要的临床价值。
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| 关 键 词： | 冠状动脉疾病 半胱氨酸 C反应蛋白质 脂蛋白(a) D-二聚体 |
Clinical value of combined detection of four items of parameters in the diagnosis of coronary heart disease |
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| LIN Zhi-fang,CEN Li-lian,KE Zun-bin,JIA Bing,LI Hai-zhu,SHUAI Hu,MEI Min.Clinical value of combined detection of four items of parameters in the diagnosis of coronary heart disease[J].Laboratory Medicine and Clinic,2008,5(13):781-782. |
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| Authors: | LIN Zhi-fang CEN Li-lian KE Zun-bin JIA Bing LI Hai-zhu SHUAI Hu MEI Min |
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| Institution: | (Department of Clinical Labo- ratory, the First People′s Hospital of Zhaoqing City ,Zhaoing 526021, China) |
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| Abstract: | Objective To explore the relationship of four items of parameters including total homocysteine （tHcy）, high sensitive C-reactive protein （hs-CRP）, lipoprotein （a） -LP （a）],D-dimer （DD） and coronary heart disease. Methods 160 patients with coronary heart disease （CHD） （CHD group） and 80 healthy people （control group） were enrolled in the investigation. The concentrations of serum tHcy, hs-CRP, LP （a） and plasma DD were detected in all subjects. Results The concentrations of serum tHcy, hs-CRP, LP （a） and plasma DD in CHD group were significantly higher than those of control group （P〈0. 05）. Conclusion Combined detection of serum tHcy, hs-CRP, LP （a） and plasma DD has very important clinical value in the prophylaxis, early diagnosis and dynamic monitoring of coronary heart disease. |
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| Keywords: | coronary disease cysteine C-reactive protein lipoprotein（a） D-dimer |
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