应用微波技术行后半规管阻塞术的实验研究

目的 :探讨应用微波技术行后半规管阻塞术的可行性。方法 :应用微波技术对 2 0只豚鼠行后半规管阻塞术 ,观察术前、术后豚鼠眼震电图 (ENG) ,听性脑干反应 (ABR)及形态学的变化。结果 :术后第 1天豚鼠正弦摆动刺激时术侧眼震反应减弱 ;术后第 3天双侧眼震恢复对称 ;术后 30 d冰水实验结果显示两耳能引出对称性眼震 ;术后 ABR阈值无明显改变 ;术后 6 0 d病理切片证实后半规管完全阻塞而耳蜗 Corti器和壶腹嵴正常。结论 :应用微波技术行后半规管阻塞术是对后半规管阻塞术的一种有意义的改进方法。

Posterior semicircular canal occlusion with microwave assisted technique in guinea pigs

Objective:To study the effectiveness of posterior semicircular canal occlusion with microwave assisted technique.Method:Posterior semicircular canal occlusion with microwave assisted technique was performed in 20 guinea pigs.Electronystagmography (ENG) and auditory brainstem response (ABR) were recorded preoperatively and postoperatively.Morphological changes were observed under light microscopy.Result:Left and right nystagmus returned symmetrical on the 3rd postoperavtive day.Two ears showed normal symmetrical nystagmus to icc water stimulation on preoperation and the 30th postoperative day.There were no significant changes of the thresholds of ABR before and after surgery.Histopathological findings revealved that posterior semicircular canal was completely occluded,and that Organ of Corti and crista ampullaris were normal.Conclusion:Posterior semicircular occlusion with microwave technique is suggested as an effective and safe treatment for the benign paroxysmal positional vertigo.