| Inhibition of T cells by direct contact with macrophages after murine amputation injury |
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| 作者姓名： | 梁华平 王正国 |
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| 作者单位： | [1]ResearchInstituteofSurgery,DapingHospital,ThirdMilitaryMedicalUniversity,Chongqing400042,China [2]Resear,DapingHospital,ThirdMilitaryMedicalUniversity,Chongqing400042,China |
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| 基金项目： | This project was supported by National Natural Science Foundation of China (No.39170744) |
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| 摘 要： | Objective To determine whether mac-rophages post trauma have inhibitory effect onnormal T cells via direct cell to cell contact. Methods A murine amputation injurymodel was used,macrophages were harvest-ed from abdominal cavity and treated with mi-tomycin-C to abrogate the secretion of cyto-kines.Separation of T cells from splenocytesin normal mice was performed using nylon
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| 关 键 词： | 截肢 巨噬细胞 T细胞 抑制 |
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