Propranolol (Inderal) and clonidine (Catapressan) in the prophylactic treatment of migraine |
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Authors: | Børre Kåss Knut Nestvold |
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Institution: | Department of Neurology, Akershus Central County Hospital, University of Oslo, Nordbyhagen, Norway |
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Abstract: | Twenty-one patients continued a double-blind crossover study to compare the prophylactic effect on migraine of propranolol and clonidine. The daily dosage of propranolol and clonidine was 160 mg and 100 μg, respectively. Statistical analysis did not show any significant difference between the two drugs in respect to headache or nausea. The number of sickleave days and the use of symptomatic drugs were both less on propranolol treatment than on clonidine, but there was no statistically conclusive difference. |
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Keywords: | Clonidine comparative trial double-blind study migraine prophylactic treatment propranolol |
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