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Serotonin 2A receptor-like immunoreactivity is detected in astrocytes but not in oligodendrocytes of rat spinal cord
Authors:Maxishima M  Shiga T  Shutoh F  Hamada S  Maeshima T  Okado N
Affiliation:Neurobiology Laboratory, Institute of Basic Medical Sciences, University of Tsukuba, 305-8575, Tsukuba, Japan.
Abstract:The distribution of the serotonin 2A (5-HT2A) receptor in glial cells in the white matter of rat spinal cord was immunohistochemically examined with specific antibodies against the 5-HT2A receptor. 5-HT2A receptor-like immunoreactivity was detected in astrocytes that were identified by an antibody against the glial fibrillary acidic protein. In contrast, 5-HT2A receptor-like immunoreactivity was not observed in oligodendrocytes.
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