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First total synthesis of a new phenylpropanoid glycoside: natural cytotoxic compound from Cirsium japonicum
Authors:Hong-Bo Dong  Ming Hou  Wen-Bo Ma  Jing-Xia Zhang  Zhe-Yu Li  Hong-Bing Luo
Affiliation:1. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, Chinadonghongbo@cdu.edu.cnbloodwhenseeme@163.com;4. Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610052, China;5. College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China
Abstract:Abstract

Phenylpropanoid glycoside compound 1, the natural anti-tumor compound isolated from the erial parts of Cirsium japonicum, was first totally synthesized using easily available materials in short, convenient route with overall yield of 13.9%.
Keywords:Total synthesis  phenylpropanoid glycoside  natural product
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