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Antioxidant phenolic acids from the leaves of Armeniaca sibirica
Authors:Ya-Nan Wu  Wei Wang  Guo-Dong Yao  Xue-Feng Jiang
Institution:1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;2. Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China;3. BAIFENG Pharmaceutical Co., Ltd., Shenyang 110016, China;4. Collaborating Laboratory of Therapeutic Material Basis and Application of Traditional Chinese Medicine, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:Abstract

Phytochemical investigation of the leaves of Armeniaca sibirica (L.) Lam. led to the isolation of two new phenolic acids (12), together with eight known compounds (310) from the ethanol extracts of this plant. Structures of these compounds were elucidated through detailed spectroscopic analyses, using 1D-NMR and 2D-NMR in combination with HR-EI-MS techniques. All the compounds were evaluated for their antioxidant capabilities in vitro using 2, 2′-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS), 1, 1′-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assays, and ferric-reducing antioxidant power (FRAP) methods.
Keywords:Armeniaca sibirica  phenolic acids  antioxidant activity  neuroprotective effect
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