New Lycopodium alkaloids from Phlegmariurus squarrosus |
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| Authors: | Fei Liu Liao-Bin Dong Xiu Gao Xing-De Wu Juan He Li-Yan Peng |
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| Affiliation: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;2. University of the Chinese Academy of Sciences, Beijing 100049, China |
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| Abstract: | Four new Lycopodium alkaloids (1–4), together with 15 known ones, were isolated from club moss Phlegmariurus squarrosus. Notably, 8α-hydroxylycojapodine A (1) was the first derivative of lycojapodine A (5) which was a novel C16N-type Lycopodium alkaloid with an unprecedented 6/6/6/7 tetracyclic ring system. Their structures were elucidated based on the spectroscopic data, including 1D and 2D NMR techniques. |
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| Keywords: | Phlegmariurus squarrosus Lycopodium alkaloids 8α-hydroxylycojapodine A 8β-acetoxy-12β-hydroxy-epidihydrolycopodine 8β-acetyllycoposerramine-U 11β-acetoxyl-N-methylhuperzine B |
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