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Two new sesquiterpene glucosides from the leaves of Nicotiana tabacum
Authors:Xin Feng  Jun-Song Wang  Jun Luo
Affiliation:Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing, 210009, China
Abstract:Two new sesquiterpene glycosides, 11R,12-dihydroxy-6(7)-spirovetiven-8-one-9-O-β-d-glucopyranoside (1) and rishitin M1-13-O-β-d-glucopyranoside (2), have been isolated from the leaves of Nicotiana tabacum. Their structures were established by spectroscopic methods including 1H, 13C, and 2D NMR. The absolute configuration of the side chain in compound 1 was determined as R by NOESY and NOE difference spectra.
Keywords:Nicotiana tabacum  sesquiterpene glycoside  absolute configuration  spirovetiven  rishitin  Solanaceae
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