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Two new steroidal glycosides from Cynanchum amplexicaule
Authors:Gang Chen  Sha Yi  Hui-Ming Hua  Xuan Lu
Affiliation:1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang , 110016 , China;2. Key Laboratory of Structure-Based Drug Design &3. Discovery, Ministry of Education, Shenyang Pharmaceutical University , Shenyang , 110016 , China;4. Department of Instrumental Analysis , Shenyang Pharmaceutical University , Shenyang , 110016 , China
Abstract:Two new C21 steroidal glycosides were isolated from the EtOAc fraction of Cynanchum amplexicaule. Their structures were elucidated as amplexicogenin d-3-O-β-d-cymaropyranoside (1) and stauntogenin -3-O-α-l-oleandropyranosyl-(1 → 4)-O-β-d-digitoxopyranosyl-(1 → 4)-O-β-d-oleandropyranoside (2) by spectroscopic analysis including 1D and 2D NMR experiments.
Keywords:Cynanchum amplexicaule  C21 steroidal glycosides  2,6-dideoxy-pyranoses
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