A new eudesmane sesquiterpene glycosides from Liriope muscari |
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| Authors: | Chang Jiang Zhi-Hua Liu Li Li Bin-Bin Lin Fan Yang |
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| Affiliation: | 1. Department of Resources Science of Traditional Chinese Medicines , China Pharmaceutical University , Nanjing , 210009 , China;2. Key Laboratory of Modern Chinese Medicines (Ministry of Education), China Pharmaceutical University , Nanjing , 210009 , China;3. Peking Union Medical College, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences , Beijing , 100193 , China;4. Key Laboratory of Modern Chinese Medicines (Ministry of Education), China Pharmaceutical University , Nanjing , 210009 , China |
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| Abstract: | A new eudesmane sesquiterpene glycoside, ophiopogonoside B (1), along with five known compounds, ophiopogonoside A (2), ruscogenin-1-O-[β-d-glucopyranosyl (1 → 2)]-[β-d-xylopyranosyl (1 → 3)]-β-d-fucopyranoside (3), palmitic acid (4), palmitic acid glyceride (5), and β-sitosterol-d-glucopyranoside (6),was isolated from the tuberous roots of Liriope muscari (Decn.) Bailey (Liliaceae). Their structures were confirmed by 1D and 2D NMR spectroscopy. Among them, compounds 1, 2, 4, and 5 were the first reported from the genus Liriope. Ophiopogonoside B (1) showed moderate inhibitory activity to glycogen phosphorylase a. |
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| Keywords: | Liliaceae Liriope muscari ophiopogonoside B sesquiterpene glycosides |
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