Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice |
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| Authors: | X-W Yang H Zhang M Li L-J Du Z Yang S-Y Xiao |
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| Institution: | 1. State Key Laboratory of Natural &2. Biomimetic Drugs, School of Pharmaceutical Sciences, and Medical and Healthy Analysis Center , Peking University , Beijing, 100083, China xwyang@mail.bjmu.edu.cn;4. Biomimetic Drugs, School of Pharmaceutical Sciences, and Medical and Healthy Analysis Center , Peking University , Beijing, 100083, China;5. Laboratory of Pharmaceutical Science, Department of Biological Science and Biotechnology , Tsinghua University , Beijing, 100084, China;6. The Administrative Centre for China's Agenda 21, Ministry of Science and Technology , Beijing, 100089, China |
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| Abstract: | Six alkaloids (1–6) have been isolated from the fruits of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang, two of which are new compounds, identified as 2-undecyl-4(1H)-quinolone (4) and 1-methyl-2-undecanone-10′-4(1H)-quinolone (5); the known compounds were identified as rutaecarpine (1), evodiamine (2), 1-methyl-2-undecyl-4(1H)-quinoline (3) and 2-undecanone-10′-4(1H)-quinolone (6). Compounds 1–5 were evaluated for their acute toxicity. |
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| Keywords: | Evodia rutaecarpa (Juss) Benth var bodinaieri (Dode) Huang 2-Undecyl-4(1H)-quinolone 1-Methyl-2-undecanone-10′-4(1H)-quinolone |
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