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Chain terpenoids isolated from cultures of basidiomycete Phellinus sp.
Authors:Jiang-Bo He  Xiao-Man Lv  Zheng-Hui Li  Shen Zhang  Dong-Bao Hu  Rong-Hua Yin
Affiliation:1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;2. School of Medicine, Kunming University, Kunming 650214, China;3. College of Elementary Medicine, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China
Abstract:Two new sesquiterpenoids (phellinuins H and I), together with five known compounds, were isolated from cultures of mushroom Phellinus sp. Their structures were elucidated based on comparison of nuclear magnetic resonance and MS data and those reported in the literature. All of these compounds were tested for cytotoxicity against five cancer cell lines (HL-60, SMMC-721, A-549, MCF-7, and SW-480).
Keywords:mushroom  Phellinus sp  sesquiterpenoids  phellinuins H and I  cytotoxicity
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