Polyphenolic compounds from the leaves of Koelreuteria paniculata Laxm |
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Authors: | Wen-Han Lin Zhi-Wei Deng Hai-Ming Lei Hong-Zheng Fu Jun Li |
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Affiliation: | 1. National Research Laboratory of Natural and Biomimetic Drugs , Peking University , Beijing, 100083, China;2. Analytical and Testing Center , Beijing Normal University , Beijing, 100875, China |
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Abstract: | From the fresh leaves of Koelreuteria paniculata Laxm (Sapindaceae), four new compounds, named ethyl p-trigallate (1), 3"-O-galloyl-4'-O-galloyl-4-O-galloyl-gallic acid (2), ethyl p-heptagallate (3) and 3"-galloylquercitrin (4), together with 12 known compounds namely catechin (5), galloylepicatechin (6), isorhamnetin (7), kaempferol-3-O-arabinopyranoside (8), quercetin-3'-O- g -D-arabinopyranoside (9), quercitrin (10), methyl p-digallate (11), methyl m-digallate (12), p-digalloyl acid (13), m-digalloyl acid (14), hyperin (15) and kaempferol-3-O- f -L-rhamnoside (16) were isolated by extensive column chromatographic separation. Their structures were elucidated on the basis of chemical and spectroscopic methods. Compound 9 was not reported previously with pyranoside of arabinose at C-3'. Compounds 4 and 9 possessed the activity for PTK inhibition. |
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Keywords: | Koelreuteria Paniculata Leaves Galloyl Derivatives Flavonoids |
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