Triterpene saponins from the leaves of Ilex kudingcha |
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Authors: | Li Tang Yong Jiang Xiao-Ming Tian Si-Xiang Zhou |
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Affiliation: | 1. School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing, 100083, China;2. College of Life and Environmental Sciences , Minzu University of China , Beijing, 100081, China;3. School of Pharmaceutical Sciences , Peking University Health Science Center , Beijing, 100083, China |
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Abstract: | Three new triterpene saponins, ilekudinosides T–V (1–3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-β-d-glucopyranosyl-(1 → 3)-[α-l-rhamnopyranosyl-(1 → 2)]-α-l-arabinopyranosyl-3β,19α-dihydroxy-urs-12(13)-en-28,20β-lactone (1), 3-O-β-d-glucopyranosyl-(1 → 3)-[α-l-rhamnopyranosyl-(1 → 2)]-α-l-arabinopyranosyl-3β,19α-dihydroxy-12-ethoxy-urs-13(18)-ene-28,20β-lactone (2), 3-O-β-d-glucopyranosyl-(1 → 3)-[α-l-rhamnopyranosyl-(1 → 2)]-α-l-arabinopyranosyl-3β,19α-dihydroxy-11-oxo-urs-13(18)-ene-28,20β-lactone (3), respectively. The structures of compounds 1–3 were elucidated on the basis of the chemical and spectroscopic evidence, and the structures of known compounds were identified by comparison of their spectroscopic data with those reported in the literature. |
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Keywords: | Ilex kudingcha triterpenoid saponin ilekudinosides T–V |
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