A novel triterpenoid saponin from Polygala tenuifolia Willd. |
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| Authors: | Tun-Hai Xu Gang Lv Sheng-Xiu Xie Hong-Feng Zhao Dong Han |
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| Affiliation: | 1. Department of Traditional Chinese Medicine Chemistry, School of Traditional Chinese Medicine , Beijing University of Chinese Medicine , Beijing, 100102, China;2. School of Traditional Chinese Medicine , Xinjiang University of Medicine , Urumchi, 830054, China;3. Institute of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine and Material Medica of Jilin Province , Changchun, 130021, China |
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| Abstract: | A new triterpenoid saponin, tenuifoside A, was isolated together with three known triterpenoid saponins 2, 3, and 4 from the roots of Polygala tenuifolia Willd. With the help of chemical and spectral analyses (IR, MS, 1D-NMR, and 2D-NMR), the structure of the new saponin was elucidated as 3-O-β-d-glucopyranosyl presenegenin 28-O-β-d-xylopyranosyl-(1 → 3)-β-d-xylopyranosyl-(1 → 4)-[β-d-apiofuranosyl-(1 → 3)]-α-l-rhamnopyranosyl-(1 → 2)-[4-O-p-methoxycinnamoyl]-[α-l-rhamnopyranosyl-(1 → 3)]-β-d-fucopyranosyl ester (1). Three known triterpenoid saponins (2–4) were identified on the basis of spectroscopic data. |
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| Keywords: | Polygala tenuifolia Willd radix polygala triterpenoid saponin tenuifoside A |
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