Three new triterpenoid saponins from the seeds of Aesculus turbinata |
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| Authors: | Xiu-Wei Yang Jing Zhao Masao Hattori |
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| Institution: | 1. The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science , Peking University , Beijing, 100083, China xwyang@bjmu.edu.cn xwyang@hsc.pku.edu.cn;3. The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science , Peking University , Beijing, 100083, China;4. Institute of Natural Medicines, Toyama Medical &5. Pharmaceutical University , 2630 Sugitani, Toyama, 930-0194, Japan |
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| Abstract: | Three new triterpenoid saponins, named isoescins VIIa (1), VIa (2), and VIIIa (3), were isolated from the seeds of Aesculus turbinata and identified by spectroscopic analysis and chemical hydrolysis. Their structures were established as 21β-O-tigloyl-28-O-acetylprotoaescigenin 3β-O-β-d-galactopyranosyl(1 → 2)]β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIIa, 1), 21β-O-(2-methylbutyryl)-28-O-acetylprotoaescigenin 3β-O-β-d-glucopyranosyl(1 → 2)] β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIa, 2), and 21β-O-angeloyl-28-O-acetylbarringtogenol C 3β-O-β-d-glucopyranosyl(1 → 2)] β-d-glucopyranosyl(1 → 4)]-β-d-glucopyranosiduronic acid (Isoescin VIIIa, 3). |
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| Keywords: | Hippocastanaceae Aesculus turbinata isoescin VIa isoescin VIIa isoescin VIIIa |
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