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Two new steroidal saponins from the roots of Cynanchum limprichtii |
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| Authors: | Jia-Chuan Liu Li-Li Yu Ming-Xu Tang Xiao-Jie Lu Dan Zhao Hai-Feng Wang |
| Affiliation: | 1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;2. Key Laboratory of Structure-Based Drug Design &3. Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China;4. College of Basic Science, Jinzhou Medical University, Jinzhou 121001, China;5. College of Basic Science, Jinzhou Medical University, Jinzhou 121001, China |
| Abstract: | AbstractAs a part of our continuing research for bioactive constituents from Cynanchum limprichtii Schltr., two new C21 steroidal glycosides limproside A (1) and limproside B (2) were isolated from the roots of Cynanchum limprichtii. Their structures were elucidated on the basis of 1D- and 2D-NMR spectroscopic data as well as HR-ESI-MS analysis. The cytotoxicity of two compounds against two selected human cancer cell lines was assayed. |
| Keywords: | Asclepiadaceae Cynanchum limprichtii steroidal glycoside limproside cytotoxicity |