The genetic association between alpha-2-macroglobulin (A 2 M) gene deletion polymorphism and low serum A 2 M concentration in overweight/obese Thais |
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| Authors: | WILAIWAN RUGSARASH RUNGSUNN TUNGTRONGCHITR SONGSAK PETMITR BENJALUCK PHONRAT PRANEET PONGPAEW TALABPORN HARNROONGROJ |
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| Affiliation: | 1. Faculty of Tropical Medicine Mahidol University, Department of Tropical Nutrition and Food Science, Ratchathewi, Bangkok, Thailand;2. Faculty of Tropical Medicine Mahidol University, Department of Clinical Tropical Medicine, Ratchathewi, Bangkok, Thailand |
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| Abstract: | AbstractThe study subjects were 192 overweight and obese Thais (BMI > 25.00 kg/m 2 ), and 103 Thai controls (BMI = 18.50–24.99 kg/m 2 ), whose ages ranged from 18–60 years. All subjects were evaluated for serum Alpha-2-macroglobulin (A 2 M), globulin, albumin concentration, and polymorphic variation in the A 2 M gene. Serum A 2 M and albumin were significantly lower in the overweight/obese group ( P |
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| Keywords: | A 2 M deletion polymorphism genetic association overweight/obese serum A 2 M |
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