Microbial transformation of acetyl-11-keto-boswellic acid by Cunninghamella elegans |
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| Authors: | Xiu-Lan Xin Hua Huo Liang Chen Jian Li Peng-Wu Zheng |
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| Affiliation: | 1. College of Bioengineering, Beijing Polytechnic, Beijing, 100029, China;2. Northern Hospital, General Hospital of PLA Shenyang Military Area Command, Shenyang, 11031, China;3. School of Pharmaceutical Science, Jiangxi Science and Technology Normal University, Nanchang, 330039, China |
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| Abstract: | Microbial biotransformation of acetyl-11-keto-boswellic acid by Cunninghamella elegans AS 3.1207 was carried out, and totally four transformed products were isolated. On the basis of the extensive spectral data, their structures were characterized as 7β-hydroxy-11-keto-boswellic acid (1), 7β,30-dihydroxy-11-keto-boswellic acid (2), 7β,16α-dihydroxy-3-acetyl-11-keto-boswellic acid (3), and 7β,15α,21β-trihydroxy-3-acetyl-11-keto-boswellic acid (4), respectively. Among them, products 1 and 2 are the new compounds. |
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| Keywords: | biotransformation boswellic acid Cunninghamella elegans AS 3.1207 triterpenes |
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