Two new guaiane sesquiterpene lactones from the aerial parts of Artemisia vulgaris |
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| Authors: | Tran Thi Hong Hanh Le Thi Thuy Hang Phan Thi Thanh Huong Nguyen Quang Trung Tran Van Cuong Nguyen Van Thanh |
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| Affiliation: | 1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam;2. Graduate University of Science and Technology, VAST, Hanoi, Vietnam;3. Center for Training, Consultancy &4. Technology Transfer, VAST, Hanoi, Vietnam;5. Center for High Technology Development, VAST, Hanoi, Vietnam |
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| Abstract: | AbstractTwo new guaiane sesquiterpene lactones, vulgarolides A and B (1 and 2), were isolated from Artemisia vulgaris aerial parts using various chromatographic separations. The structure elucidation was performed by combination of spectroscopic experiments including 1D and 2D NMR, HR ESI MS, and CD. Their in vitro cytotoxic activities against five human cancer cell lines were also evaluated using SRB method. |
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| Keywords: | Artemisia vulgaris Asteraceae guaiane sesquiterpene lactone |
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