Two new xanthones from Artocarpus obtusus |
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| Authors: | Najihah Hashim Mohd A. Sukari Abdul M. Ali Noorjahan B. Alitheen Rosea Go |
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| Affiliation: | 1. Department of Chemistry , Universiti Putra Malaysia 43400 UPM , Serdang, Selangor, Malaysia;2. Department of Cell and Molecular Biology , Universiti Putra Malaysia 43400 UPM , Serdang, Selangor, Malaysia;3. Department of Biology , Universiti Putra Malaysia 43400 UPM , Serdang, Selangor, Malaysia |
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| Abstract: | Two new xanthones, pyranocycloartobiloxanthone A (1) and dihydroartoindonesianin C (2), were isolated from the stem bark of Artocarpus obtusus Jarrett by chromatographic separation. Their structures were determined by using spectroscopic methods and comparison with known related compounds. Pyranocycloartobiloxanthone A (1) showed strong free radical scavenging activity by using DPPH assay as well as cytotoxicity towards K562, HL-60, and MCF7 cell lines. |
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| Keywords: | Artocarpus obtusus Moraceae pyranocycloartobiloxanthone A dihydroartoindonesianin C cytotoxicity |
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