Three new diterpenoid alkaloids from the roots of Aconitum duclouxii |
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| Authors: | Tian-Peng Yin Le Cai Jian-Min He Jian-Wei Dong Hai-Xian Fang Hao Zhou |
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| Institution: | 1. Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;2. School of Resource and Environment, Baoshan University, Baoshan 678000, China |
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| Abstract: | Three new C19-diterpenoid alkaloids, ducloudines C (1), D (2), and E (3), were isolated from the roots of Aconitum duclouxii. Their structures were established on the basis of extensive spectroscopic analyses. Ducloudine C (1) is the first aconitine-type C19-diterpenoid alkaloid with a C = O group at C-3 and a C = C bond between C-1 and C-2. All compounds were tested for their biological activities against one pathogenic fungi and two pathogenic bacteria. |
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| Keywords: | Aconitum duclouxii diterpenoid alkaloids biological activity ducloudines C–E |
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