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Pushing the boundaries in liver graft utilisation in transplantation: Case report of a donor with previous bile duct injury repair
Affiliation:Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom
Abstract:IntroductionLiver transplantation is a recognised treatment for extensive bile duct injuries with secondary biliary cirrhosis or recurring sepsis. However, there have been no reports of successful liver transplantation from a donor who sustained a previous bile duct injury.Presentation of caseHere we discuss the case of a liver transplant from a 51-year-old brain dead donor who had suffered a Strasberg E1 bile duct injury and had undergone a Roux-en-Y hepaticojejunostomy 24 years prior to donation. The liver was successfully recovered and transplanted into a 56-year-old male recipient with end stage liver disease consequent to alpha 1 antitrypsin deficiency. The graft continues to function well 36 months post-transplant, with normal liver function tests and imaging revealing a patent hepaticojejunostomy.DiscussionThe potential associated vascular injuries should be identified during bench preparation whilst the management of biliary reconstruction at the time of transplant should follow the principles of biliary reconstruction in cases with biliary injuries, extending the hilar opening into the left duct.ConclusionThis case highlights the successful utilisation of a post bile duct injury repair liver, employing an experienced procurement team and careful bench assessment and reconstruction.
Keywords:Extended criteria donor  Liver transplantation  Organ procurement  Bile duct injury
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