Prevalence and symptomatic correlates of interpersonal trauma in South Korean outpatients with major depressive disorder |
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| Affiliation: | 1. Department of Psychiatry, Yong-In Mental Hospital, Yongin, Republic of Korea;2. Institute of Mental Health, Hanyang University, Seoul, Republic of Korea;3. Department of Psychiatry, Hanyang University Medical School, Seoul, Republic of Korea;4. Department of Psychiatry, Hanyang University Guri Hospital, Guri, Republic of Korea;1. Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, Republic of Korea;2. Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, Republic of Korea;3. SureCare Medical Centre, Kowloon, Hong Kong;4. Department of Microbiology, Madras Medical Mission, Chennai, India;5. Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan;6. Institute for Medical Research, Kuala Lumpur, Malaysia;7. Antimicrobial Resistance Surveillance Reference Laboratory, Research Institute for Tropical Medicine, Manila, Philippines;8. University of Colombo, Colombo, Sri Lanka;9. Siriraj Hospital, Mahidol University, Bangkok, Thailand;10. National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan;11. Faculty of Medicine, University of Medicine and Pharmacy, Ho Chi Minh, Vietnam;12. King Saud University, Riyadh, Saudi Arabia;13. Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;14. Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea;1. Department of UrologyNational Police HospitalSeoulKorea;2. Genitourinary Disease Oriented Translational ResearchSeoulKorea;3. Department of UrologySamsung Medical CenterSungkyunkwan University School of MedicineSeoulKorea |
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| Abstract: | BackgroundThere is growing evidence that exposure to severe interpersonal trauma (IPT) has a pivotal role in the development and manifestation of depression. However, it is not clearly understood whether patients with major depressive disorder (MDD) have specifically increased prevalence of IPT than other non-interpersonal traumatic events and whether those with IPT have unique symptom profile within depressed groups. In this study, we investigated the prevalence of past traumatic events and symptomatic features of treatment-seeking outpatients with MDD.MethodsA consecutive sample of 111 South Korean outpatients with MDD was recruited on their first visit to a psychiatric department of a university-affiliated hospital. Participants completed the Life Events Checklist (LEC), the Symptom Checklist-90-Revised (SCL-90-R), Beck Depression Inventory (BDI), State–Trait Anxiety Inventory (STAI), Dissociative Experience Scale (DES) and Impact of Event Scale-Revised (IES-R). The prevalence of past traumatic events on LEC was compared to medical outpatients.ResultsCompared to medical outpatients, MDD patients had significantly higher rates of IPT (physical and sexual) but not other traumatic events of non-interpersonal origin such as accidents or disaster. Compared to MDD patients without IPT (n = 44, 40%), those with IPT (n = 67, 60%) had higher subscale scores on hostility in SCL-90-R, as well as greater depressive and post-traumatic symptoms. However, multivariate analysis revealed that the best model to discriminate those with IPT was interaction of depressive and posttraumatic symptoms.LimitationsLimitations include sample characteristics (treatment-seeking outpatients) and possible effects of comorbid conditions, which were not investigated.ConclusionsClinicians managing individuals with depressive disorder need to include the assessment of lifetime IPT and its impact on presenting symptoms. |
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