Evaluation of antibiofilm and mechanical properties of new nanocomposites based on acrylic resins and silver vanadate nanoparticles |
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| Institution: | 1. Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, USP—University of São Paulo, Ribeirão Preto, SP, Brazil;2. Postgraduate Program in Materials Science and Engineering—PPG-CEM, Federal University of São Carlos—UFSCAR, São Carlos, SP, Brazil;3. Department of Natural Sciences, GPQM —Research Group of Materials Chemistry, Federal University of São João del Rei—UFSJ, São João del Rei, MG, Brazil;4. Laboratory of Solid State Chemistry, State University of Campinas (UNICAMP), Campinas, Brazil;1. Professor and Director, Advanced Specialty Education Program in Prosthodontics, School of Dentistry, Loma Linda University, Loma Linda, Calif;2. Faculty, Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia;1. University Institute of Chemical Technology, North Maharashtra University, Jalgaon, MS, India;2. Institute of Chemical Technology, Matunga, Mumbai, MS, India;1. Department of Prosthodontics, Dental School, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil;2. Department of Clinics, Pediatric Dentistry, School of Dentistry, Fluminense Federal University, Niteroi, Rio de Janeiro, Brazil;3. Institute of Microbiology Professor Paulo de Góes, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil;1. Department of Life Sciences, University of Mumbai, Santacruz (E), Mumbai 400 098, India;2. Chemistry Division, Bhabha Atomic Research Centre, Mumbai 400 085, India;3. Molecular Biology Division, Bhabha Atomic Research Centre, Mumbai 400 085, India;4. School of Environment & Sustainable Development, Central University of Gujarat, Gandhinagar 382 030, Gujarat, India;1. PhD candidate, Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas (UFPEL), Pelotas-RS, Brazil;2. MSc candidate, Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas (UFPEL), Pelotas-RS, Brazil;3. PhD candidate, Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas (UFPEL), Pelotas-RS, Brazil;1. Researcher assistant, Department of Cariology, Restorative Sciences and Endodontics, University of Michigan School of Dentistry, Ann Arbor, Mich;4. Professor, Dental Materials Laboratory, Academic Area of Dentistry, Autonomous University of Hidalgo State, Pachuca, Mexico;5. Associate professor, Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas (UFPEL), Pelotas, Rio Grande do Sul, Brazil;6. Associate professor, Graduate Program in Dentistry, Pelotas Dental School, Federal University of Pelotas (UFPEL), Pelotas, Rio Grande do Sul, Brazil |
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| Abstract: | ObjectiveThe purpose of this study was evaluate, for the first time, the impact of incorporation of nanostructured silver vanadate (β-AgVO3) in antibiofilm and mechanical properties of dental acrylic resins (poly(methyl methacrylate), PMMA).DesignThe β-AgVO3 was synthesized and characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and microanalysis (SEM/EDS). Resins specimens were prepared with 0–10% wt.% β-AgVO3 and characterized by SEM, XRD and optical microscopy. The antibiofim activity of the samples against Candida albicans and Streptococcus mutans was investigated by XTT reduction test, colony-forming units (CFUs), and confocal laser scanning microscopy (CLSM). The flexural strength, hardness, and surface roughness of the samples containing β-AgVO3 were compared with the pure PMMA matrix.ResultsThe incorporation of 10% β-AgVO3 significantly reduced the metabolic activity of C. albicans and S. mutans (p < 0.05). There was a reduction in microbial load (CFU/mL) of microorganisms for the different concentrations used (p < 0.05), which was confirmed by confocal microscopy. The addition of β-AgVO3 did not change the mechanical properties of hardness and surface roughness of the resins (p > 0.05). However, flexural strength decreased with the addition of amounts greater than 1% (p < 0.05).Conclusionsβ-AgVO3 additions in dental acrylic resin may have an impact on inhibition of biofilm of main microorganisms associated with dental prostheses. However, the viability of clinical use should be evaluated in function of changed promoted in some mechanical properties. |
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| Keywords: | Nanomaterials Silver vanadate Acrylic resin Antibiofilm properties Mechanical behavior |
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