针灸治疗溃疡性结肠炎的Meta分析

目的:评价针灸治疗溃疡性结肠炎的有效性和安全性。方法:检索近10年针灸干预溃疡性结肠炎的随机对照试验或临床对照试验,并对文献结果进行Meta分析。结果:共11篇临床研究文献入选。对11项研究结果进行异质性检验,结果χ2=8.55,P=0.67,采用固定效应模型进行统计分析,合并后OR=3.82,95%可信区间为2.65-5.52,菱形位于中间线的右侧,经Z检验,Z=7.14,P<0.01,试验组和对照组疗效比较差异有非常显著性意义,即针灸治疗组疗效明显优于对照组,痊愈率高于对照组。结论:针灸治疗溃疡性结肠炎疗效优于西药,且副作用少,具有安全性。

Meta-analysis on acupuncture and moxibustion for treatment of ulcerative colitis

OBJECTIVE: To assess the effectiveness and safety of acupuncture and moxibustion for treatment of ulcerative colitis. METHODS: Randomized controlled trials or clinical controlled trials of acupuncture and moxibustion for interfere of ulcerative colitis in recent 10 years were reviewed and Meta-analysis was made for the literature results. RESULTS: Altogether 11 papers of clinical study were enrolled. Heterogeneous tests were conducted for the results of the 11 studies, as a result, chi2 = 8.55, P = 0.67. The fixed effect model was used for statistical analysis, after combination OR = 3.82, confidence interval of 95% was 2.65-5.52. The rhombus was located at the right side of the medium line. After Z test, Z = 7.14, P < 0.01, the therapeutic effect and the cured rate in the treatment group were significantly higher than those of the control group. CONCLUSION: The therapeutic effect of acupuncture and moxibustion on ulcerative colitis is superior to that of western medicine with safety and less adverse reactions.