卵巢环管状性索间质瘤2例报告并文献复习

目的：探讨卵巢环管状性索间质瘤的发病原因、发病机制、临床特点.方法：分析2例卵巢环管状性索间质瘤的临床资料并复习文献.结果：环管状性索间质瘤在卵巢肿瘤中占0.06%,属于低度恶性.其CA-125值可正常或略高,血清MIS值检测可作为其诊断的一种标记物.约1/3患者伴Peutz-Jeghers综合征（PJS）.可分泌较高水平的雌激素和少量的孕激素.诊断主要依靠病理.结论：提高对卵巢环管状性索间质瘤的认识,熟悉其发病原因、发病机制、临床特点等,可减少误诊及漏诊.

Ovarian Vasicentric Sexual Funicular Interstitialoma Two Cases Report and Literature Review

Objective:To explore the pathogenic factors,pathogeny and clinical features of ovarian vasicentric sexual funicular interstitialoma(OVSFI).Method:The clinical data of 2 cases of OVSFI was analysed and literatures review.Result:OVSFI accounted for 0.06% in ovarian cancer.It was low malignant.Its value of CA-125 was normal or slightly higher.Its serum MIS could be a diagnostic marker.About 1/3 cases could complicated with Peutz-Jeghers syndrome.OVSFI could secrete a high level of estrogenic hormone and a little pregestogen.To diagnose OVSFI was by pathology of OVSFI mainly.Conclusion:To improve the understanding and familiar the pathogenic factors,pathogeny and clinical features of OVSFI can reduce the misdiagnosis and missed diagnosis.