| PCR检测沙眼衣原体与习惯性流产和女性不孕相关性研究 |
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| 引用本文： | 周宁,于萍,陈诵芬,谢智农,尹格平. PCR检测沙眼衣原体与习惯性流产和女性不孕相关性研究[J]. 中国优生与遗传杂志, 1995, 3(6): 22-24 |
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| 作者姓名： | 周宁 于萍 陈诵芬 谢智农 尹格平 |
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| 作者单位： | 山东济南军区总医院妇产科，山东医科大学生理学教研室 |
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| 摘 要： | 本文应用聚合酶链反应技术（ＰＣＲ），对１２０例不孕和１００例查体妇女的宫颈内膜标本进行沙眼衣原体检测，以了解女性沙眼衣原体感染与自发流产的关系，并与一般细胞培养法进行了比较。结果：不孕妇女中沙眼衣原体感染率为１８．３％，显著高于对照组（８％Ｐ＜０．０５），并且自发流产３次、４次的妇女沙眼衣原体阳性率明显高于对照组（Ｐ＜０．０１）．敏感性也较一般培养法高（Ｐ＜０．０１）。本研究提示：沙眼衣原体感染与自发性习惯性流产关系十分密切，而且ＰＣＲ法在检测沙眼衣原体感染方面较一般培养法更敏感、快速，是早期诊断生殖道沙眼衣原体感染的一项有价值的方法。
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| 关 键 词： | 沙眼衣原体感染 习惯性流产 女性不孕 自发流产 培养法 相关性研究 查体 一般 敏感 原件 |
Detection of Chlamydia trachomatis by PCR in the endocervices of woman with recurrent spontaneous abortions and tubular infertility |
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| .Zhou Ning,et al.. Detection of Chlamydia trachomatis by PCR in the endocervices of woman with recurrent spontaneous abortions and tubular infertility[J]. Chinese Journal of Birth Health & Heredity, 1995, 3(6): 22-24 |
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| Authors: | .Zhou Ning et al. |
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| Abstract: | From July 1993 to January 1995,endocervical samples from 120 woman with tubular infertility and 100 control groups were detected by PCR and compare with cultrue to investigate the relationship between Chlamydia trachomatis and spontaneous abortion.Result:Using PCR.22 of the 120 women(18.3%)with tubular infertility had positive for cervical chlamydia trachomatis infections and the infectious rates of recurrent spontaneous aboutions groups were higher than control group.(P<0.01).The polymerase chain reaction appeared to be more sensitive and more rapid than culture in detecting Chlamydia trachomatis.The infections of Chlamydia trachomatis were more related with recurrent sptaneous abortions. |
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| Keywords: | Chlamydia trachomatis PCR Endocervical samples Abortion Infertility. |
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