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Novel antiviral agents: phosphoramidates or mono/di/tri-phosphate esters of carbocyclic adenosine analogues |
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| Abstract: | The patent application describes new compounds, their preparation processes and methods for their use in treating viral infections (particularly hepatitis B) and retroviral infections (particularly HIV). The anti-HIV activity in MT4 cells is claimed to be in the range pM to μM. |
| Keywords: | carbocyclic nucleoside analogues diphosphate esters hepatitis B virus HIV monophosphate esters phosphoramidates reverse transcriptase inhibitor triphosphate esters |