慢性肺原性心脏病对左心室功能的影响

目的研究慢性肺原性心脏病(肺心病)右心功能损害对左心室功能的影响。方法分析21例慢性肺心病的超声心动图,以二尖瓣A/E比值为指标观察左心室舒张功能;测量EF、CO、SV、CI、FS作为观察左心室收缩功能的指标;并测量左室心腔内径及计算左室心肌重量指数。结果研究发现肺心病组二尖瓣A/E比值为1.14±0.14,与对照组比较P<0.01。EF、CO、SV、CI、FS分别为61.90±11.82,4.47±0.89,56.71±13.70,63.20±0.58,与对照组比较P>0.05。心肌重量指数83.76±19.10,与对照组无统计学差异。结论慢性肺心病①左室舒张早期充盈受损;②本研究未发现左室收缩功能减退;③不伴有左心腔扩大或左室心肌肥厚。

The Effect of Chronic Lung Original Heart Disease to Left Ventricle Function

Objective To study the influence of right ventricular dysfunction caused by chronic pulmonary heart disease to left ventricular function. Method Analyzing 21 cases echocardiography of chronic pulmonary heart disease,observing diastolic function of left ventricle with A/E ratio of mitral valve as index;measuring EF、CO、SV、CI、FS as index of observing the systolic function of left ventricle;Measuring the diameter of left ventricular cavity and calculating the weight of cardiac muscle in left ventricular.Result The research shows that theA/E ratio of mitral valve in the group of pulmonary heart disease is 1.14±0.14,P<0.01 comparing with the control group.EF is 61.90±11.82,CO is 4.47±0.89,SV is 56.71±13.70,CI is 63.20±0.58,and FS is P>0.05 comparing with the control group.The weight of cardiac muscle is 83.76±19.10,the same as the control group in statistics.Conclusion Chronic pulmonary heart disease;①the left ventricular injured in the forepart of diastolic filling;②the systolic function of left ventricle has not been found weakened in the research;③there is no expansion of left ventricular cavity or hypertrophy of cardiac muscle in left ventricular.