糖尿病与甲状腺激素水平异常相关性研究

目的 探讨糖尿病与甲状腺激素的关系.方法 选取糖尿病患者98例,另选取健康人群40例作为对照组.抽取受检者空腹静脉血5ml,测定其T3、T4、FT3、FT4、TSH、rT3水平,并分析与糖尿病类型、病情、病程的关系.结果 (1)糖尿病与对照组的关系:Ⅰ型DM组和2型DM组T3、T4、FT3、FT4水平均低于对照组,rT3高于对照组(P＜0.05)；1型DM组T3、T4、FT3、FT4水平均低于2型DM组,rT3高于2型DM组(P＜0.05).(2)病情与TH关系:7％ ～ 10％组、＞10％～13％组和HbA1c＞ 13％组的T3、FT3及TSH均低于HbA1c ＜7％组(P＜0.05).(3)病程与TH关系:随着病程的延长T3、FT3呈下降趋势,rT3呈上升趋势(P＜0.05).结论糖尿病患者存在甲状腺激素水平异常,监测其甲状腺激素对评价患者糖尿病病情及病程具有重要意义.

The clinical significance of thyroid hormones test using in diabetes mellitus

Objective To explore the clinical significance of thyroid hormones test using in diabetes mellitus （DM）. Methods 98 cases with DM and 40 health people were selected. The serum T3, T4, FT3, FT4, TSH, rT3 levels were tested to analy the relativity of DM and TH. Results The type 2 DM＇s and type 1 DM＇s T3 ,T4, FT3 , FT4 levels were much lower than those of the control group, while the rT3 level was higher （ P 〈 0.05 ） ; and the type 1 DM was the lowest one （P 〈 0.05 ）. In group 7% - 10%, Group 〉 10% - 13% and Group HbA1 c 〉 13 % T3 , FT3 and TSH levels were lower than Group HbA1 c 〈 7% （ P 〈 0.05 ）. With DM extension, FT3 and T3 declined, while rT3 ascended （ P 〈 0. 05 ）. Conclusion DM patients are always with the abnormal of TH level, so monitoring the TH level is important for evaluating the DM patients＇ state and course.