Surveillance following radical or partial nephrectomy for renal cell carcinoma |
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Authors: | John S. Lam John T. Leppert Robert A. Figlin Arie S. Belldegrun |
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Affiliation: | (1) Department of Urology, David Geffen School of Medicine at University of California, Los Angeles, 10833 Le Conte Avenue, 66-118 CHS, Box 951738, 90095-1738 Los Angeles, CA, USA |
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Abstract: | Renal cell carcinoma (RCC) is the most lethal of the common urologic malignancies, with approximately 40% of patients eventually dying of cancer progression. Approximately one third of patients present with metastatic disease and up to 50% treated for localized disease have a recurrence. Although the prognosis generally is poor in these patients, some may respond to immunotherapy and a subset of patients who develop solitary metastases can achieve long-term survival. Therefore, the timely identification of recurrences following surgical extirpation is imperative in the treatment of patients. |
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