Clostridium difficile-associated reactive arthritis in two children |
| |
Authors: | Löffler Helga A Pron Benedicte Mouy Richard Wulffraat Nico M Prieur Anne-Marie |
| |
Affiliation: | Department of Pediatric Rheumatology, H?pital Necker-Enfants Malades, Université Paris V, 149 rue de Sèvres, 75743 Paris, France. |
| |
Abstract: | In adults, reactive arthritis (ReA) following Clostridium difficile-enterocolitis has been documented. In children, only one case of C. difficile-associated ReA has been reported. We now describe two other cases of ReA associated with C. difficile in children. The characteristics of ReA due to C. difficile appear to be similar in adults and children. Both children show polyarthritis after an episode of diarrhoea with positive stool cultures for C. difficile. Arthritis is asymmetrical with a self-limiting course. Nonsteroidal antiinflammatory drug (NSAID) therapy is sufficient. One case is remarkable because of its prolonged course of ReA despite NSAID therapy, and its association with the presence of HLA-B27 antigen. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|