18F-FDG PET/CT与CT检测鼻咽癌颈部转移淋巴结的对比研究

目的比较18F-FDG PET/CT与CT显像对鼻咽癌颈部转移淋巴结的诊断价值,为放射治疗靶区的勾画提供参考。方法40例病理确诊为鼻咽癌的患者,放疗前均行PET/CT及CT检查,并用双盲法将PET/CT与同期的CT诊断结果进行比较。结果CT检出咽旁间隙淋巴结2个,最大直径15.0 mm;PET/CT检出咽后及咽旁间隙淋巴结淋巴结各8个,最大直径4.0~15.0 mm,淋巴结摄取FDG均增高,SUV最大值2.9~14.1;CT检出双侧颈部淋巴结48个,最大直径8.0~25.0 mm,PET/CT检出70个(包括CT检出的48个淋巴结),最大直径4.0~25.0 mm;除1个淋巴结外,淋巴结摄取FDG均增高,SUV最大值3.4~11.2。结论18F-FDG PET/CT显像对鼻咽癌颈部转移淋巴结的诊断优于CT,对放疗靶区的勾画有较大的指导作用。

Comparative analysis of 18F-FDG PET/CT and CT scan in detecting neck lymph node metastasis from nasopharyngeal carcinoma

Objective To compare the difference from diagnosis value of 18F-FDG PET/CT(18F-fluorodeoxyglucose position emission tomography) with that of computed tomography (CT) in detecting metastasis lymph node in neck from Nasopharyngeal carcinoma(NPC),provide reference for designing the radiotherapy target region.Methods Forty cases of squamous cell carcinoma of NPC,underwent wholebody 18F-FDG PET/CT and CT scans before radiotherapy,PET/CT images were analyzed visually and compared with CT images with double-blind method.Results CT detecting 2 lymph nodes of parapharyngeal space,diameter maximum was 15.0 mm,PET/CT detecting 8 lymph nodes of pharynx back and 8 lymph nodes of pharynx neighbour,diameter maximum was 4.0-15.0 mm,lymph nodes were heighten FDG uptake,range of their SUV max was 2.9-14.1;CT detecting 48 lymph nodes of double necks,diameter maximum was 8.0-25.0 mm.PET/CT detecting 70 lymph nodes(including CT detecting 48 lymph nodes),diameter maximum was 4.0-25.0 mm.All the lymph nodes were heighten FDG uptake but except one,range of their SUV max was 3.4-11.2.Conclusion 18F-FDG PET/CT scan is more valuable than CT in detecting metastasis lymph node in neck for nasopharyngeal carcinoma and also helpful for sketching the radiotherapy target region.