High prevalence of Clostridium difficile diarrhoea during intensive chemotherapy for disseminated germ cell cancer. |
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| Authors: | H Nielsen G Daugaard M Tvede B Bruun |
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| Affiliation: | Department of Clinical Microbiology, Rigshopitalet, Copenhagen, Denmark. |
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| Abstract: | A prospective, consecutive study of the aetiology of treatment-associated diarrhoea was conducted in 25 patients with disseminated germ cell cancer treated with intensive chemotherapy. Clostridium difficile was isolated in 45% of the diarrhoea episodes, which makes this species the most important bacterial pathogen in the development of clinically significant diarrhoea in this group of immunocompromised patients. |
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