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First report of occurrence of choroid plexus papilloma and medulloblastoma in the same patient
Authors:Siddharth Banka  Richard Walsh  Marie-Anne Brundler
Institution:(1) Department of Neurosurgery, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK;(2) Department of Histopathology, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK
Abstract:Introduction Choroid plexus papilloma is a benign epithelial brain tumour showing a striking predilection for infants and occurring most frequently in the lateral and fourth ventricles. Medulloblastoma, on the other hand, is a primitive neuroectodermal tumour and is the most frequent malignant brain tumour of the posterior fossa in children. In this study, we report a metachronous occurrence of choroid plexus papilloma and medulloblastoma in the same patient, which has not been reported before to the best of our knowledge. Case report The authors describe the case of a girl who presented with an atypical choroid plexus papilloma on the posterior wall of the left lateral ventricle at 3 months of age that was resected completely. She was followed up regularly after surgery and made good progress with normal development. At 8 years of age, she presented with right cerebellar medulloblastoma. Discussion The authors review literature for incidence and aetiology of the two tumours.
Keywords:Choroid plexus papilloma  Medulloblastoma
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