先天性白内障大鼠的繁殖性能及生长发育的研究

目的 了解先天性白内障大鼠的生物学特性。方法 用原种群繁殖扩群，观察繁殖性能及仔鼠的生长发育。结果 白内障大鼠、小眼白内障组与正常对照组间的产仔数和离乳数均无显著性差异（p>0.05）；体重比，在出生后第2周时白内障大鼠生长速度比小眼白内障组和正常对照组体重大（p>0.05）；雄性间比较，2 周时白内障大鼠组比其它二组生长速度快，4周时更为明显（p>0.01）；雄雌间比较，5周时白内障大鼠组和正常对照组雄雌间生长速度出现差异（p>0.01），小眼白内障组在第6周时生长速度才出现差异（p>0.01）。结论 白内障疾病基因对大鼠的繁殖率没有影响，而对仔鼠的生长速度有一定的影响。

THE STUDY THE PERFORMANCE AND GROWTH AND DEVELOPMENT OF THE CONGENITAL CATARACT

Objective To understand the biological characteristics of congenital cataract rats. Methods Expanding populations by breeding with the original group, then to observe reproductive performance and offspring growth and development. Results There was no significant differenceboth in the birth rate and the weaning number between the normal controlled group and cataract and microphthalmos cataract groups (p>0.05). Compared with other two groups,the cataract group had heavier weight at the second week after birth.In comparison between males of different groups, the cataract group growed faster at first two weeks after birth and the difference in weight was more obvious at fourth week after bieth(p<0.01) .In comparison between sexes, there was significant differencesin in weight between male and famale in the cataract group and the control group at the fifth week after birth (p<0.01), while the microphthalmos cataract group had significant differences at the sixth week (p<0.01). Conclusion Cataract gene in rats did not affect their reproductive rate, while the growth rate of pups had a certain impact.