| 竹节参不同提取部位预处理对冠脉结扎诱导大鼠急性心肌缺血损伤的影响 |
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| 引用本文： | 贺海波,许佳,王洪武,何治,徐媛青,狄国杰,李守超,张长城,袁丁.竹节参不同提取部位预处理对冠脉结扎诱导大鼠急性心肌缺血损伤的影响[J].第三军医大学学报,2011,33(14):1462-1466. |
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| 作者姓名： | 贺海波 许佳 王洪武 何治 徐媛青 狄国杰 李守超 张长城 袁丁 |
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| 作者单位： | 宜昌,三峡大学医学院中药药理实验室,湖北,443002 |
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| 基金项目： | 国家自然科学基金(31070314,30873383)~~ |
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| 摘 要： | 目的 研究竹节参不同提取部位预处理对冠脉结扎诱导大鼠急性心肌缺血损伤的保护作用.方法 将50只实验大鼠按完全随机设计分组法分为假手术组、模型组和竹节参不同提取部位组;竹节参不同提取部位组大鼠分别灌胃给予竹节参不同提取部位(乙酸乙酯部位、正丁醇部位和水提部位),给药7 d后制作大鼠急性心肌缺血模型,术后12 h记录大鼠心...
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| 关 键 词： | 竹节参 提取物 急性心肌缺血 保护作用 |
Effects of preconditioning with different fractions extracted from Panax japonicus C.A.Mey on acute myocardial ischemia in rats induced by ligation of left anterior descending branch |
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| He Haibo,Xu Jia,Wang Hongwu,He Zhi,Xu Yuanqing,Di Guojie,Li Shouchao,Zhang Changcheng,Yuan Ding.Effects of preconditioning with different fractions extracted from Panax japonicus C.A.Mey on acute myocardial ischemia in rats induced by ligation of left anterior descending branch[J].Acta Academiae Medicinae Militaris Tertiae,2011,33(14):1462-1466. |
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| Authors: | He Haibo Xu Jia Wang Hongwu He Zhi Xu Yuanqing Di Guojie Li Shouchao Zhang Changcheng Yuan Ding |
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| Institution: | He Haibo,Xu Jia,Wang Hongwu,He Zhi,Xu Yuanqing,Di Guojie,Li Shouchao,Zhang Changcheng,Yuan Ding(Laboratory of Pharmacology of Traditional Chinese Medicine,Medical Science College of Three Gorges University,Yichang,Hubei Province,443002,China) |
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| Abstract: | Objective To investigate the protective effects of preconditioning with different fractions extracted from Panax japonicus C.A.Mey on acute myocardial ischemia in rats induced by ligating of the left anterior descending branch(LAD).Methods Fifty Wistar rats were evenly and randomly divided into a sham group,a model group and three treatment groups.The treatment groups were given different fractions extracted from Panax japonicus C.A.Mey,i.g.,an ethyl acetate fraction,an n-butyl alcohol fraction and a water ... |
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| Keywords: | Panax japonicus C A Mey extract fraction acute myocardial ischemia protective effect |
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