| 509例儿童肾活检病理及临床分析 |
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| 引用本文： | 谢丹凤,李秋.509例儿童肾活检病理及临床分析[J].第三军医大学学报,2011,33(16):1736-1739. |
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| 作者姓名： | 谢丹凤 李秋 |
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| 作者单位： | 重庆医科大学附属儿童医院肾脏免疫科,重庆,400014 |
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| 基金项目： | 重庆市自然科学基金重点项目(CSTC2009BA5080); 重庆市卫生局重点项目(2009-1-34)~~ |
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| 摘 要： | 目的探讨儿童肾小球疾病病理特点及其与临床表现的关系。方法回顾性分析2007年1月至2010年5月在重庆医科大学附属儿童医院进行肾活检的509例患儿病理及临床资料,比较原发性肾小球疾病和继发性肾小球疾病的病理和临床特征。结果①509例肾活检患儿中,原发性肾小球疾病315例,继发性肾小球疾病184例,遗传性肾小球疾病和肾血管疾病分别为6例、2例,肾小管间质性肾炎2例。②与原发性肾小球疾病组比较,继发性肾小球疾病组平均受检年龄大于原发性肾小球疾病组(10.54±2.72)岁vs(8.62±3.28)岁],受检时平均病程较原发性肾小球疾病组短(30.00 dvs60.00 d)。③原发性肾小球疾病组最常见的临床表现和病理类型分别为肾病综合征、系膜增生性肾小球肾炎(M sPGN),继发性肾小球疾病组中分别为过敏性紫癜性肾炎和M sPGN。④近年来本院受检儿童肾小球疾病构成比发生变化。原发性肾小球疾病仍为最常见的肾小球疾病,最常见的病理类型是M sPGN和IgA肾病。孤立性血尿及狼疮性肾炎比例增加。结论肾脏病理检查技术的开展促进了肾小球疾病诊疗水平的提高,同时该技术可能也直接影响肾小球疾病住院构成比的变化。
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| 关 键 词： | 肾小球疾病 病理学 临床特征 儿童 |
Pathological characteristics and clinical manifestations in 509 children with renal diseases from a single unit |
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| Xie Danfeng,Li Qiu.Pathological characteristics and clinical manifestations in 509 children with renal diseases from a single unit[J].Acta Academiae Medicinae Militaris Tertiae,2011,33(16):1736-1739. |
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| Authors: | Xie Danfeng Li Qiu |
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| Institution: | Xie Danfeng,Li Qiu(Department of Nephroimmunology,Children's Hospital,Chongqing Medical University,Chongqing,400014,China) |
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| Abstract: | Objective To explore the relationship between the pathological characteristics and clinical manifestations of renal glomerular diseases in children.Methods Retrospective analysis was performed using the pathological and clinical data of 509 children with renal diseases to compare primary glomerular disease and secondary glomerular disease in terms of pathological characteristics and clinical manifestations.These children received renal biopsy in the Children's Hospital of Chongqing Medical University from J... |
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| Keywords: | renal glomerular disease pathology clinical characteristics children |
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