| 枸杞子提取物对人淋巴细胞表面IL-2R表达的影响 |
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| 引用本文： | 杜守英,钱玉昆. 枸杞子提取物对人淋巴细胞表面IL-2R表达的影响[J]. 中华微生物学和免疫学杂志, 1995, 0(3) |
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| 作者姓名： | 杜守英 钱玉昆 |
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| 作者单位： | 北京医科大学免疫教研室 100083(杜守英)，北京医科大学免疫教研室 100083(钱玉昆) |
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| 摘 要： | 研究了枸杞子提取物(LBr)对白细胞介素2受体(IL—2R)表达的影响。用FACS法和APAAP法研究了LBr作用3天对PHA活化扁桃体单个核细胞(TMNC)表面IL—2Rα、IL—2Rβ表达的影响,发现合适浓度的LBr(1.9ng/ml～7.8μg/ml)可促进IL—2R的表达。对α链表达的促进作用于第1天即出现,第3天达高峰,第5天始明显下降以至消失。
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| 关 键 词： | 枸杞子提取物 扁桃体单个核细胞 白细胞介素2受体 碱性磷酸酶-抗碱性磷酸酶法 |
EFFECT OF THE EXTRACTION OF LYCIUM BARBARUM ON THE IL-2R EXPRESSION OF HUMAN LYMPHOCYTES |
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| Du Shouying,Qian Yukun. EFFECT OF THE EXTRACTION OF LYCIUM BARBARUM ON THE IL-2R EXPRESSION OF HUMAN LYMPHOCYTES[J]. Chinese Journal of Microbiology and Immunology, 1995, 0(3) |
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| Authors: | Du Shouying Qian Yukun |
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| Affiliation: | Du Shouying,Qian Yukun Department of Immunology,Beijing Medical University,Beijing 100083 |
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| Abstract: | The effect of the extraction of Lycium Barbarum (LBr) on the IL-2R expression of human lymphocytes was studied. The results showed that:LBr could promote the expression of IL-2 receptors. IL-2 receptors (a and (3 chains) on themembrane of TMNC cells were assessed with APAAP and FACSmethod on the 3rd day. We discovered that suitable dose of LBr(1.9ng/ml-7.8ug/ml) could increase the expression of IL-2Ra and IL-2RB extensively. The enhancement on IL-2Ra appeared on the 1st day and reached the peak on the 3rd day,then gradually decreased. |
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| Keywords: | Extraction of LB(LBr) Tonsilarmononuclear cell (TMNC) Interleukin-2 receptor(IL-2R) Alka-phosphorase-antialkaphosphorasemethod (APAAP) FACSmethod |
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