三种不同方法用于紧急避孕的临床观察

目的:观察三种方法用于紧急避孕的临床效果。方法:选择接收无保护性生活或避孕失败72小时内要求紧急避孕的健康育龄妇女354例。组Ⅰ(119例),单次口服米非司酮25mg(25mg/片);组Ⅱ(120例),左炔诺酮首次口服0.75mg(0.75mg/片),间隔12小时再服0.75mg;组Ⅲ(115例):放置含铜IUD。以服药或放置IUD后月经来潮为成功标准,以Dixon表格计算避孕有效率。结果:三组共有3例失败,均显著低于预期妊娠数(10.945,9.516,8.461)(P<0.05);避孕有效率分别为81.7%、89.5%、100%。对下次月经影响均较轻微(P>0.05),组Ⅰ副反应发生率明显低于组Ⅱ(P<0.01)。结论:三种方法用于紧急避孕安全、有效、简便。

Three Different Approaches for Emergent Contraception

Objective: To evaluate the effectiveness of three kinds of approaches for emergent contraception. Methods: 354 healthy women who experienced unprotected sexual intercourse or failed contraception wthin 72 hours and asked for emergent contraception were divided into three groups. 119 Women in group I took a single dose of 25㎎ (25㎎/tab) mifepristone. 120 cases in group Ⅱ took 0.75㎎ (0.75㎎/tab) LNG and took the same dose at twelfth hour. 115 cases in group Ⅲ were inserted intrauterine device (IUD). The contraceptive effective rate was calculated by Dixon table, according to standard of the menstruation after treatment. Results: There were 3 failed cases in three groups. The effective rates were 81.7 %, 89.5% and 100%, respectively. Three approaches had less impact on next menses (P﹥0.05). The incidence of side effects in the group I was less than that in goup II (P<0.01) Conclusion: Three methods are effective, safe.