持续皮下胰岛素输注治疗糖尿病高血糖的临床分析

目的探讨持续皮下胰岛素输注强化治疗高血糖的效果及其对糖尿病并发症发生发展的影响。方法笔者采用胰岛素泵和多次皮下注射胰岛素方法强化治疗高血糖。结果多数患者在置泵第2天血糖即明显下降，缩短了院时间。持续皮下胰岛素输注法与多次皮下注射胰岛素法相比，前者将血糖控制在良好范围内的时间明显缩短，胰岛素用量明显减少，且低血糖发生率也明显减少，血糖变异系数明显减小。结论持续皮下胰岛素输注较皮下注射控制血糖效果好，可避免长时间的高胰岛素血症，减轻胰岛素抵抗，减少慢性并发症的发生。

Clinical Analysis on Intensive Therapy of Continuous Subcutaneous Insulin Injection for Hyperglycemia of Diabetes Mellitus

Objective To investigate the effect of intensive therapy with continuous subcutaneous insulin injection for hyperglycemia and complication of diabetes mellitus. Methods Diabetic hyperglycemia was treated with intensive therapy by insulin pump and subcutaneous injection ,and the curative effects were compared. Results Compared with subcutaneous insulin injection, short-term intensive therapy of diabetic hyperglycemia with insulin pump improved blood glucose control, decreased insulin dose, lowered the rates of hypoglycemia, diminished the coefficient of variation of blood glucose, and shortened the hospitalization time. Conclusions Continuous subcutaneous insulin injection have a good curative effect for hyperglycemia. It can avoid long time hyperinsulinemia,lessen insulin resistance and decrease the complications of diabetes mellitus.