Hormonal treatments of sexual unresponsiveness in postmenopausal women: a comparative study |
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Authors: | M. G. T. DOW Senior Clinical Psychologist D. M. HART Consultant Gynaecologist C. A. FORREST Senior Registrar in Obstetrics Gynaecology |
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Affiliation: | Gartnavel Royal Hospital, Glasgow G12 OXH;Stobhill General Hospital, Glasgow G21 3UW, Scotland, UK |
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Abstract: | Summary. Forty postmenopausal women, referred for hormone replacement therapy and all of whom reported a significant concern about a decline in their sexual interest, were randomly allocated to one of two hormone implant treatment groups: either oestradiol (50 mg) alone, or oestradiol (50 mg) and testosterone (l00mg). Comparison between the two groups as a whole revealed no significant differences on any measure, both treatments being associated with a significant reduction in the severity of psychological, somatic and vasomotor symptoms, and with a significant improvement in sexual interest and responsiveness. Similar effects were also observed in patients who denied, pretreatment, any concurrent dyspareunia. Although it is not possible to identify the reasons for change, the results indicate no advantages of supplementary testosterone administration over oestradiol alone for sexually unresponsive postmenopausal women. |
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