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恶性肿瘤稳定期与转移期血小板变化
引用本文:刘占伟,张永亮,黄金. 恶性肿瘤稳定期与转移期血小板变化[J]. 武警医学, 2011, 22(11): 946-947,951
作者姓名:刘占伟  张永亮  黄金
作者单位:武警山西总队医院综合科,太原,030006;郑州市儿童医院,453000
摘    要: 目的 探索恶性肿瘤由稳定期发展至转移期的血小板变化规律,筛选转移期的血小板截断值.方法 回顾性分析30例经标准治疗后由稳定期发展至转移期的癌症患者转移前后的血小板计数,采用配对样本1检验分析血小板变化与发生转移的关系;通过绘制ROC曲线图,找出转移期血小板的临界值.结果 患者转移期血小板计数增高,稳定期和转移期血小板差异有统计学意义(P<0.05);转移期血小板截断值为271×109/L,其灵敏度为64%,特异度为95%.结论 恶性肿瘤由稳定期发展至转移期时血小板计数呈明显升高趋势.血小板计数<271×109/L时,其发生转移的可能性较小;而血小板计数>271×109/L时,应考虑病情恶化的可能性.

关 键 词:恶性肿瘤  稳定期  转移期  血小板计数  

Changes of platelets in cancer patients with tumor metastasis
LIU Zhanwei,ZHANG Yongliang,HUANG Jin. Changes of platelets in cancer patients with tumor metastasis[J]. Medical Journal of the Chinese People's Armed Police Forces, 2011, 22(11): 946-947,951
Authors:LIU Zhanwei  ZHANG Yongliang  HUANG Jin
Affiliation:LIU Zhanwei~1,ZHANG Yongliang~1,and HUANG Jin~2.1.Shanxi Provincial Corps Hospital of Chinese People's Armed Police Forces,Taiyuan 030006,China,2.Zhengzhou Children's Hospital,Zhengzhou 453000
Abstract:Objective To study the variation regularity of platelets in cancer patients from the stable stage to metastasis after standard treatment and to screen the cutoff value of platelets in tumor metastasis.Methods The platelets ol thirty cancer patients from the stable stage to tumor metastasis after standard treatment were retrospectively analyzed.Platelet counts relative to metastasis were analyzed by paired-samples t-test.The cutoff value of platelets during tumor metastasis was identifyed by drawing the ROC ...
Keywords:cancer  stable stage  metastasis  platelet count  
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