| 外源性硫化氢对人胃癌细胞凋亡的影响 |
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| 引用本文： | 孙东升,张力. 外源性硫化氢对人胃癌细胞凋亡的影响[J]. 中国医疗前沿, 2010, 5(13): 16-16,78 |
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| 作者姓名： | 孙东升 张力 |
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| 作者单位： | 孙东升,SUN Dong-sheng(齐齐哈尔医学院机能教研室,161006);张力,Zhang Li(哈尔滨医科大学病理生理教研室,150081) |
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| 摘 要： | 目的探讨外源性硫化氢（H2S）对人胃癌SGC-7901细胞凋亡的影响。方法体外培养人胃癌SGC-7901细胞,分为两组,对照组细胞正常培养,硫氢化钠（NaHS）组使用浓度为800μmol/L的NaHS作用于胃癌细胞12h,流式细胞仪检测细胞凋亡率。结果 NaHS组细胞早期凋亡率、晚期凋亡率均显著高于对照组（p〈0.05）。结论外源性H2S可以促进人胃癌细胞的凋亡。
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| 关 键 词： | 硫化氢 胃癌细胞 凋亡 |
Effects of Extrogenous Hydrogen Sulfide on Apoptosis of Human Gastric Cancer Cells |
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| SUN Dong-sheng,Zhang Li. Effects of Extrogenous Hydrogen Sulfide on Apoptosis of Human Gastric Cancer Cells[J]. China Healthcare Innovation, 2010, 5(13): 16-16,78 |
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| Authors: | SUN Dong-sheng Zhang Li |
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| Affiliation: | .(Functional Experiment Department of Qiqihaer Medical College,Qiqihaer,161006,China ) |
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| Abstract: | Objective To explore the effects of extrogenous hydrogen sulfide on apoptosis of human gastric cancer SGC-7901 cells.Methods Human gastric cancer SGC-7901 cells were cultured in vitro and were divided into two groups including control group and NaHS group.NaHS group cells were treated with 800μmol/L NaHS for 12 hours.The apoptotic rates were determined by flow cytometry（FCM）.Results Either early apoptotic rate or late apoptotic rate were significantly higher than control（p〈0.05）,respectively.Conclusion Extrogenous hydrogen sulfide could promote the apoptosis of human gastric cancer cells. |
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| Keywords: | Hydrogen sulfide Gastric cancer cells Apoptosis |
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