复方磺胺嘧啶锌涂膜、湿润烧伤膏用于烧伤创面效果对比观察

目的观察复方磺胺嘧啶锌涂膜与湿润烧伤膏治疗烧伤浅Ⅱ度、深Ⅱ度、感染创面的疗效。方法将同一烧伤病人随机分为左右(治疗组、对照组)或上下(治疗组、对照组)两组创面,共45例(即90个创面)。治疗组用复方磺胺嘧啶锌涂膜涂于创面,对照组用湿润烧伤膏涂于另一创面,观察两组的止痛效果、创面炎症控制、抑菌效果、创面愈合时间及换药次数。结果止痛效果对照组优于治疗组(P<0.01);换药后创面炎症控制方面治疗组优于对照组;Ⅱ度创面治疗组用药前细菌培养阳性率是40%,治疗中降至10%,对照组用药前细菌培养阳性率为36.6%,治疗中升至60%,两组间比较具有差异有统计学意义(P<0.05),感染创面治疗组用药后细菌定量少于对照组(P<0.05);创面愈合时间:治疗组(12±3.1)d,对照组(15±2.4)d,深Ⅱ度创面,治疗组(27±3.5)d,对照组(50±8.3)d,治疗组优于对照组(P<0.05);换药次数,治疗组明显少于对照组(P<0.05)。结论湿润烧伤膏在止痛效果方面优于复方磺胺嘧啶锌涂膜,复方磺胺嘧啶锌涂膜在预防、控制创面感染,加快创面愈合等方面优于湿润烧伤膏。

Comparison between Agent SD-Ag-Zn and Exposed Moist Burn Ointment in Treatment 0f Burn Wounds

Objective To observe the efficacies of agent SD-Ag-Zn and exposed moist burn ointment in the treatment of burn wounds.Methods Ninety burn wounds of 45 patients were divided into treatment group and control group,i.e.the agent of SD-Ag-Zn was applied to the treatment group while the exposed moist burn ointment to the control group.Analgesic effect,wound inflammation and healing time were investigated.Results More intensive analgesic effect appeared in the control group than in the treatment(P<0.01).Positive-rate of bacteria culture went down from 40% to 10% in those of the treatment group with burn of degree Ⅱ,while it rose from 36.6% to 60.0% in the counterparts of the control group(P<0.05).Wound healing time was 12.0±3.1 days in the treatment group and 15.0±2.4 days in the control group.As for those with burn of deep degree Ⅱ,burn wound healing time was 27.0±3.5 days(treatment group) and 50.0±8.3 days(control group)(P<0.05).Conclusion Exposed moist burn ointment is superior to the agent of SD-Ag-Zn in analgesic effect,while the agent of SD-Ag-Zn is superior to moist exposed burn ointment in preventing and controlling wound infection and promoting wound healing.