| 急性淋巴细胞性皮肤白血病 |
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| 引用本文： | 曹育春,李慎秋,陈辉,陈兴平,刘继红.急性淋巴细胞性皮肤白血病[J].临床皮肤科杂志,2008,37(6):376-378. |
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| 作者姓名： | 曹育春 李慎秋 陈辉 陈兴平 刘继红 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院皮肤科,湖北 武汉,430030 |
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| 摘 要： | 报告1例急性淋巴细胞性皮肤白血病.患者女,17岁.右胫前肿块2个月余,右大腿出现紫红色结节、躯干出现紫红色浸润性斑块1个月余,偶有疼痛和瘙痒.血常规检查正常.皮损组织病理榆查示真皮浅层有一狭窄无浸润带,在真皮和皮下组织可见大小不一的单一核细胞浸润,部分胞核较大,深染,偶见核丝分裂.免疫组化染色结果示CD3、CD4、CD5、CD8、CD20、CD79、MPO标志均为阴性,CD68阳性,且TdT标记30%～40%单一核细胞为阳性,提示为淋巴细胞前体细胞,结合骨髓细胞学检查诊断为急性淋巴细胞白血病(ALL-L2).给予患者DOCP(吡柔比星、地塞米松、环磷酰胺及长春新碱)方案化疗2个疗程后,胫前肿块缩小变平,身体其他部位皮损均消退.
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| 关 键 词： | 白血病 皮肤 淋巴细胞性 |
A case of acute lymphocytic leukemia of skin |
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| GAO Yu-chun,LI Shen-qiu,CHEN Hui,CHEN Xing-ping,LIU Ji-hong.A case of acute lymphocytic leukemia of skin[J].Journal of Clinical Dermatology,2008,37(6):376-378. |
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| Authors: | GAO Yu-chun LI Shen-qiu CHEN Hui CHEN Xing-ping LIU Ji-hong |
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| Abstract: | A 17-year-old female patient with acute lymphocytic leukemia of skin is reported. The girl presented with a pretibial mass on right leg for 2 months, and a purple nodule on the right thigh and infiltrated plaques on the trunk for 1 month. The lesions were occasionally painful and itchy. The blood routine test was normal. The diagnosis of acute lymphocytic leukemia(ALL-L2) was confirmed by cutaneous histopathology, immunohistochemistry and bone-mallow smear. After 2 courses of DOCP treatment regimen (pirarubicin, dexamethasone, cyclophosphamide and vincristine), the lesions on the trunk and right thigh resolved. |
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| Keywords: | leukemia cutis lymphocytic |
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