用乙肝诊断试剂盒对新疆野生啮齿动物进行血清学调查

目的调查新疆野生啮齿动物的血清中乙型肝炎病毒表面抗原的存在状态.方法应用乙肝表面抗原诊断试剂盒和乙肝表面抗体诊断试剂盒,对野生啮齿动物进行了血清学调查.结果灰旱獭(Marmota baibacina)的阳性率为17.8%(24/135)、长尾黄鼠(Citellus undulatus)阳性率为17.4%(12/69)和赤颊黄鼠(Citellus erythrogenys)阳性为(8/15).结论血清学调查表明,野生啮齿动物血清中存在乙型肝炎病毒表面抗原.

Investigation on Serology in Wild Rodent with Diagnostic Kit for HBV in Xinjiang, China

Objective This paper is to investigate on hepatitis B virus (HBV) HBsAg in wild rodent in Xinjiang, China. Method The HBV HBsAg was surveyed in serum samples from captive gray marmot (Marmota baibacina),long-tailed suslik (Citellus undulatus) and red-cheeked suslik (Citellus erythrogenys) at Changji ,Manas, Shawan ,Wenquan and Jinghe in Xinjiang, China from may to august, 2003. Wild rodents were trapped and blood samples were collected to determine the prevalence of HBV HBsAg in natural populations. Result Sera from 135 gray marmot (Marmota baibacina), 69 long-tailed suslik (Citellus undulatus) and 15 red-cheeked suslik (Citellus erythrogenys) trapped from different areas in xinjiang were tested for evident of HBV HBsAg. 24 of 135 (17.8%) gray marmot were positive for HBV HBsAg, 12 of 69 (17.4%) long-tailed suslik were positive and 8 of 15 red-cheeked suslik were positive. 2 of 135 gray marmot were positive for anti-HBs of HBV and 2 of 15 red-cheeked suslik were positive. The data indicated a high prevalence in the wild rodents from the surveyed areas. The hepadnaviruses location in class was discussed. We found in the positive sera of wild rodents with many unique characteristics of HBV. Conclusion There was HBV HBsAg in sera of wild rodents.